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BHB Brianna Stubbs Ketone Esters Kieran Clarke Peter Cox Weight Loss

A Ketone Ester Drink Lowers Human Ghrelin and Appetite

November 7, 2017

A very exciting paper has been published in the Journal Obesity that shows that elevated levels of BHB (the Ketone Beta Hydroxy Butyrate) in the blood cause appetite suppression and decrease in food consumption. The work was done by Dr Brianna Stubbs at Oxford University and used a product similar to that recently released by HVMN

Some quotes from the paper.

Elevated blood BHB occurs during both exogenous and endogenous ketosis; therefore, BHB may be a direct mediator of the lower appetite and altered gut hormone levels seen in both settings

Also reducing satiety

Finally, it is important to emphasize that the levels of GLP-1 and PYY, both satiety signals, were also downregulated by acute KE administration

The paper concludes

Therefore, KE drinks offer a unique opportunity to isolate and exploit the effects of ketosis on appetite without other dietary interventions.

In the article they also add a disclaimer that

it is unclear whether Ketone Ester consumption could be used for long-term appetite control. Therefore, until any chronic effects are fully characterized, ketone supplements should not be used to replace dietary strategies for weight control.

I think that there is little risk for exogenous ketones to be used for short term interventions, many people have been on strict ketogenic diets for decades with no ill effect. I would also contend any of the theoretical issues that may arise from ketone consumption may be outweighed for people carrying excess body fat.

There are numerous anecdotal reports of users of Ketone Salts echoing these results from the research and many people are using ketone salts and will use the KE when they become commercially available to help assist in these areas.




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