Link to PUBMED Introduction: Brain glucose uptake is impaired in Alzheimer’s disease (AD). A key question is whether cognitive decline can be delayed if this brain energy defect is at least partly corrected or bypassed ...
Dr Stephen Cunnane is one of the leading researchers looking at Ketones, the ketogenic diet and Alzheimers disease and cognitive decline or impairment. If you’ve not got time to listen to the complete presentation then ...
Dr Steven Cunane has developed a PET scan for ketones. This can demonstrate areas of the brain where ketones are uptaken and being used, this can be compared to a glucose PET Scan and in ...
To view full IUBMB Life Article Introduction: The extension of life span by caloric restriction has been studied across species from yeast and Caenorhabditis elegans to primates. No generally accepted theory has been proposed to explain these observations. ...
To View PUBMED Full Article: Introduction: We propose that brain energy deficit is an important pre-symptomatic feature of Alzheimer’s disease (AD) that requires closer attention in the development of AD therapeutics. Our rationale is fourfold: ...
To view the full article Introduction: Our clinical and animal projects are closely interrelated in that we attempt to understand our human findings by studying cellular mechanisms in animal models of common cardiac diseases, including diabetes ...
To view the full article Introduction: Major depressive disorder (MDD) is characterized by depressed mood, anhedonia, low self-esteem, loss of motivation, sleep disruption, loss of appetite, and other cognitive symptoms1. Approximately 33% of patients with ...
To read the full blog… Introduction: A keto-adapted subject (who may already benefit from some Delta G arbitrage) will, under fixed work load, require less oxygen when ingesting exogenous ketones than when not. Posed as ...
To view the full article Introduction: Ketogenesis is the process by which ketone bodies (KB), during times of starvation, are produced via fatty acid metabolism. Although much feared by physicians, mild ketosis can have therapeutic ...
On the Metabolism of Exogenous Ketones in Humans Comprehensive review document by Dr Brianna Stubbs in the Journal Frontiers in Physiology Link to full paper Abstract Background and aims: Currently there is considerable interest in ...
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